Functional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation

Platelets harbor the primary reservoir of circulating plasminogen activator inhibitor 1 (PAI-1), but the reportedly low functional activity of this pool of inhibitor has led to debate over its contribution to thrombus stability. Here we analyze the fate of PAI-1 secreted from activated platelets and...

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Detalles Bibliográficos
Autores principales: Morrow, Gael B., Whyte, Claire S., Mutch, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716352/
https://www.ncbi.nlm.nih.gov/pubmed/33256381
http://dx.doi.org/10.3324/haematol.2019.230367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716352/
https://www.ncbi.nlm.nih.gov/pubmed/33256381
http://dx.doi.org/10.3324/haematol.2019.230367

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