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Functional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation
Platelets harbor the primary reservoir of circulating plasminogen activator inhibitor 1 (PAI-1), but the reportedly low functional activity of this pool of inhibitor has led to debate over its contribution to thrombus stability. Here we analyze the fate of PAI-1 secreted from activated platelets and...
Autores principales: | Morrow, Gael B., Whyte, Claire S., Mutch, Nicola J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716352/ https://www.ncbi.nlm.nih.gov/pubmed/33256381 http://dx.doi.org/10.3324/haematol.2019.230367 |
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