Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia

Regulated trafficking of G protein–coupled receptors (GPCRs) controls cilium-based signaling pathways. β-Arrestin, a molecular sensor of activated GPCRs, and the BBSome, a complex of Bardet–Biedl syndrome (BBS) proteins, are required for the signal-dependent exit of ciliary GPCRs, but the functional...

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Detalles Bibliográficos
Autores principales: Shinde, Swapnil Rohidas, Nager, Andrew R., Nachury, Maxence V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716378/
https://www.ncbi.nlm.nih.gov/pubmed/33185668
http://dx.doi.org/10.1083/jcb.202003020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716378/
https://www.ncbi.nlm.nih.gov/pubmed/33185668
http://dx.doi.org/10.1083/jcb.202003020

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