STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain

Following the detection of cytosolic double-stranded DNA from viral or bacterial infection in mammalian cells, cyclic dinucleotide activation of STING induces interferon β expression to initiate innate immune defenses. STING activation also induces LC3B lipidation, a classical but equivocal marker o...

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Detalles Bibliográficos
Autores principales: Fischer, Tara D., Wang, Chunxin, Padman, Benjamin S., Lazarou, Michael, Youle, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716379/
https://www.ncbi.nlm.nih.gov/pubmed/33201170
http://dx.doi.org/10.1083/jcb.202009128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716379/
https://www.ncbi.nlm.nih.gov/pubmed/33201170
http://dx.doi.org/10.1083/jcb.202009128

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