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Acarbose ameliorates spontaneous type-2 diabetes in db/db mice by inhibiting PDX-1 methylation
Pancreatic and duodenal homeobox (PDX)-1 is a gene that plays an important role in pancreatic development and function. Type-2 diabetes mellitus (T2DM) is a metabolic disease associated with insulin resistance and impaired islet β-cell function. There is evidence that methylation of PDX-1 plays a ro...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716388/ https://www.ncbi.nlm.nih.gov/pubmed/33236139 http://dx.doi.org/10.3892/mmr.2020.11710 |