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Metformin induces apoptosis and inhibits migration by activating the AMPK/p53 axis and suppressing PI3K/AKT signaling in human cervical cancer cells

Human cervical cancer is the fourth most common malignancy among women worldwide, and it is expected to result in 460,000 deaths per year by 2040. Moreover, patients with cervical cancer often display drug resistance and severe side effects; therefore, the development of effective novel chemotherape...

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Detalles Bibliográficos
Autores principales: Chen, Ya-Hui, Yang, Shun-Fa, Yang, Chueh-Ko, Tsai, Horng-Der, Chen, Tze-Ho, Chou, Ming-Chih, Hsiao, Yi-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716426/
https://www.ncbi.nlm.nih.gov/pubmed/33236135
http://dx.doi.org/10.3892/mmr.2020.11725