Cisplatin and carboplatin result in similar gonadotoxicity in immature human testis with implications for fertility preservation in childhood cancer

BACKGROUND: Clinical studies indicate chemotherapy agents used in childhood cancer treatment regimens may impact future fertility. However, effects of individual agents on prepubertal human testis, necessary to identify later risk, have not been determined. The study aimed to investigate the impact...

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Detalles Bibliográficos
Autores principales: Tharmalingam, Melissa D., Matilionyte, Gabriele, Wallace, William H. B., Stukenborg, Jan-Bernd, Jahnukainen, Kirsi, Oliver, Elizabeth, Goriely, Anne, Lane, Sheila, Guo, Jingtao, Cairns, Bradley, Jorgensen, Anne, Allen, Caroline M., Lopes, Federica, Anderson, Richard A., Spears, Norah, Mitchell, Rod T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716476/
https://www.ncbi.nlm.nih.gov/pubmed/33272271
http://dx.doi.org/10.1186/s12916-020-01844-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716476/
https://www.ncbi.nlm.nih.gov/pubmed/33272271
http://dx.doi.org/10.1186/s12916-020-01844-y

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