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Pan-cancer identification of clinically relevant genomic subtypes using outcome-weighted integrative clustering

BACKGROUND: Comprehensive molecular profiling has revealed somatic variations in cancer at genomic, epigenomic, transcriptomic, and proteomic levels. The accumulating data has shown clearly that molecular phenotypes of cancer are complex and influenced by a multitude of factors. Conventional unsuper...

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Detalles Bibliográficos
Autores principales: Arora, Arshi, Olshen, Adam B., Seshan, Venkatraman E., Shen, Ronglai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716509/
https://www.ncbi.nlm.nih.gov/pubmed/33272320
http://dx.doi.org/10.1186/s13073-020-00804-8