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Metformin alleviates β-glycerophosphate-induced calcification of vascular smooth muscle cells via AMPK/mTOR-activated autophagy

The aim of the present study was to investigate the effect of metformin on β-glycerophosphate-induced calcification of vascular smooth muscle cells (VSMCs) and the possible mechanisms underlying this. Using an established VSMC calcification model, VSMCs were first treated with β-glycerophosphate, be...

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Detalles Bibliográficos
Autores principales: Qiu, Xiaobo, Xu, Qing, Xu, Tianhua, Wan, Pengzhi, Sheng, Zitong, Han, Yiran, Yao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716633/
https://www.ncbi.nlm.nih.gov/pubmed/33365058
http://dx.doi.org/10.3892/etm.2020.9490