Tenascin C promotes valvular remodeling in two large animal models of ischemic mitral regurgitation

Ischemic mitral regurgitation (MR) is a frequent complication of myocardial infarction (MI) characterized by adverse remodeling both at the myocardial and valvular levels. Persistent activation of valvular endothelial cells leads to leaflet fibrosis through endothelial-to-mesenchymal transition (EMT...

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Detalles Bibliográficos
Autores principales: Hamza, Ouafa, Kiss, Attila, Kramer, Anne-Margarethe, Trojanek, Sandra, Abraham, Dietmar, Acar, Eylem, Nagel, Felix, Tretter, Verena Eva, Kitzwögerer, Melitta, Podesser, Bruno K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716900/
https://www.ncbi.nlm.nih.gov/pubmed/33258993
http://dx.doi.org/10.1007/s00395-020-00837-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716900/
https://www.ncbi.nlm.nih.gov/pubmed/33258993
http://dx.doi.org/10.1007/s00395-020-00837-5

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