Role of CK2 inhibitor CX-4945 in anti-cancer combination therapy – potential clinical relevance

BACKGROUND: Protein kinase CK2 inhibition has long been considered as an attractive anti-cancer strategy based on the following considerations: CK2 is a pro-survival kinase, it is frequently over-expressed in human tumours and its over-expression correlates with a worse prognosis. Preclinical eviden...

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Detalles Bibliográficos
Autores principales: D’Amore, Claudio, Borgo, Christian, Sarno, Stefania, Salvi, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717057/
https://www.ncbi.nlm.nih.gov/pubmed/33052585
http://dx.doi.org/10.1007/s13402-020-00566-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717057/
https://www.ncbi.nlm.nih.gov/pubmed/33052585
http://dx.doi.org/10.1007/s13402-020-00566-w

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