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Mechanistic studies of gene delivery into mammalian cells by electrical short-circuiting via an aqueous droplet in dielectric oil

We have developed a novel methodology for the delivery of cell-impermeable molecules, based on electrical short-circuiting via a water droplet in dielectric oil. When a cell suspension droplet is placed between a pair of electrodes with an intense DC electric field, droplet bouncing and droplet defo...

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Detalles Bibliográficos
Autores principales: Kurita, Hirofumi, Nihonyanagi, Hirohito, Watanabe, Yuki, Sugano, Kenta, Shinozaki, Ryuto, Kishikawa, Kenta, Numano, Rika, Takashima, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717561/
https://www.ncbi.nlm.nih.gov/pubmed/33275626
http://dx.doi.org/10.1371/journal.pone.0243361