Design, synthesis, and anticonvulsant effects evaluation of nonimidazole histamine H(3) receptor antagonists/inverse agonists containing triazole moiety

Histamine H(3) receptors (H(3)R) antagonists/inverse agonists are becoming a promising therapeutic approach for epilepsy. In this article, novel nonimidazole H(3)R antagonists/inverse agonists have been designed and synthesised via hybriding the H(3)R pharmacophore (aliphatic amine with propyloxy ch...

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Detalles Bibliográficos
Autores principales: Song, Mingxia, Yan, Rui, Zhang, Yanhui, Guo, Dongfu, Zhou, Naiming, Deng, XianQing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717691/
https://www.ncbi.nlm.nih.gov/pubmed/32529860
http://dx.doi.org/10.1080/14756366.2020.1774573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717691/
https://www.ncbi.nlm.nih.gov/pubmed/32529860
http://dx.doi.org/10.1080/14756366.2020.1774573

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