YAP-mediated mechanotransduction tunes the macrophage inflammatory response

Macrophages are innate immune cells that adhere to the extracellular matrix within tissues. However, how matrix properties regulate their function remains poorly understood. Here, we report that the adhesive microenvironment tunes the macrophage inflammatory response through the transcriptional coac...

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Detalles Bibliográficos
Autores principales: Meli, Vijaykumar S., Atcha, Hamza, Veerasubramanian, Praveen Krishna, Nagalla, Raji R., Luu, Thuy U., Chen, Esther Y., Guerrero-Juarez, Christian F., Yamaga, Kosuke, Pandori, William, Hsieh, Jessica Y., Downing, Timothy L., Fruman, David A., Lodoen, Melissa B., Plikus, Maksim V., Wang, Wenqi, Liu, Wendy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717914/
https://www.ncbi.nlm.nih.gov/pubmed/33277245
http://dx.doi.org/10.1126/sciadv.abb8471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7717914/
https://www.ncbi.nlm.nih.gov/pubmed/33277245
http://dx.doi.org/10.1126/sciadv.abb8471

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