Validation and interpretation of IGH and TCR clonality testing by Ion Torrent S5 NGS for diagnosis and disease monitoring in B and T cell cancers

Cancers of B and T lymphocytes are the most common hematologic malignancies in the US. Molecular assays for assessing clonal rearrangements of the immunoglobulin receptor (IGH) and T-cell receptor (TCR), commonly referred to as B- and T-cell clonality, as well as determination of IGH somatic mutatio...

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Detalles Bibliográficos
Autores principales: Lay, Lindsay, Stroup, Brooke, Payton, Jacqueline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718169/
https://www.ncbi.nlm.nih.gov/pubmed/33304977
http://dx.doi.org/10.1016/j.plabm.2020.e00191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718169/
https://www.ncbi.nlm.nih.gov/pubmed/33304977
http://dx.doi.org/10.1016/j.plabm.2020.e00191

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