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3D projection electrophoresis for single-cell immunoblotting

Immunoassays and mass spectrometry are powerful single-cell protein analysis tools; however, interfacing and throughput bottlenecks remain. Here, we introduce three-dimensional single-cell immunoblots to detect both cytosolic and nuclear proteins. The 3D microfluidic device is a photoactive polyacry...

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Detalles Bibliográficos
Autores principales: Grist, Samantha M., Mourdoukoutas, Andoni P., Herr, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718224/
https://www.ncbi.nlm.nih.gov/pubmed/33277486
http://dx.doi.org/10.1038/s41467-020-19738-1