Structure and dynamics of an α-fucosidase reveal a mechanism for highly efficient IgG transfucosylation

Fucosylation is important for the function of many proteins with biotechnical and medical applications. Alpha-fucosidases comprise a large enzyme family that recognizes fucosylated substrates with diverse α-linkages on these proteins. Lactobacillus casei produces an α-fucosidase, called AlfC, with s...

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Detalles Bibliográficos
Autores principales: Klontz, Erik H., Li, Chao, Kihn, Kyle, Fields, James K., Beckett, Dorothy, Snyder, Greg A., Wintrode, Patrick L., Deredge, Daniel, Wang, Lai-Xi, Sundberg, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718225/
https://www.ncbi.nlm.nih.gov/pubmed/33277506
http://dx.doi.org/10.1038/s41467-020-20044-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718225/
https://www.ncbi.nlm.nih.gov/pubmed/33277506
http://dx.doi.org/10.1038/s41467-020-20044-z

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