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Advanced co-culture 3D breast cancer model for investigation of fibrosis induced by external stimuli: optimization study
Radiation-induced fibrosis (RIF) is the main late radiation toxicity in breast cancer patients. Most of the current 3D in vitro breast cancer models are composed by cancer cells only and are unable to reproduce the complex cellular homeostasis within the tumor microenvironment to study RIF mechanism...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718236/ https://www.ncbi.nlm.nih.gov/pubmed/33277538 http://dx.doi.org/10.1038/s41598-020-78087-7 |