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Transfer learning efficiently maps bone marrow cell types from mouse to human using single-cell RNA sequencing

Biomedical research often involves conducting experiments on model organisms in the anticipation that the biology learnt will transfer to humans. Previous comparative studies of mouse and human tissues were limited by the use of bulk-cell material. Here we show that transfer learning—the branch of m...

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Detalles Bibliográficos
Autores principales: Stumpf, Patrick S., Du, Xin, Imanishi, Haruka, Kunisaki, Yuya, Semba, Yuichiro, Noble, Timothy, Smith, Rosanna C. G., Rose-Zerili, Matthew, West, Jonathan J., Oreffo, Richard O. C., Farrahi, Katayoun, Niranjan, Mahesan, Akashi, Koichi, Arai, Fumio, MacArthur, Ben D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718277/
https://www.ncbi.nlm.nih.gov/pubmed/33277618
http://dx.doi.org/10.1038/s42003-020-01463-6