Cargando…

Buprenorphine is a weak dopamine releaser relative to heroin, but its pretreatment attenuates heroin‐evoked dopamine release in rats

AIMS: The United States of America is currently in an opioid epidemic. Heroin remains the most lethal opioid option with its death rate increasing by over 500% in the last decade. The rewarding and reinforcing effects of heroin are thought to be mediated by its ability to increase dopamine concentra...

Descripción completa

Detalles Bibliográficos
Autores principales: Isaacs, Dominic P., Leman, Ryan P., Everett, Thomas J., Lopez‐Beltran, Hendrick, Hamilton, Lindsey R., Oleson, Erik B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718284/
https://www.ncbi.nlm.nih.gov/pubmed/32935483
http://dx.doi.org/10.1002/npr2.12139