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Buprenorphine is a weak dopamine releaser relative to heroin, but its pretreatment attenuates heroin‐evoked dopamine release in rats
AIMS: The United States of America is currently in an opioid epidemic. Heroin remains the most lethal opioid option with its death rate increasing by over 500% in the last decade. The rewarding and reinforcing effects of heroin are thought to be mediated by its ability to increase dopamine concentra...
Autores principales: | Isaacs, Dominic P., Leman, Ryan P., Everett, Thomas J., Lopez‐Beltran, Hendrick, Hamilton, Lindsey R., Oleson, Erik B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718284/ https://www.ncbi.nlm.nih.gov/pubmed/32935483 http://dx.doi.org/10.1002/npr2.12139 |
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