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Inhibition of LTβR-signalling activates Wnt-induced regeneration in lung

Lymphotoxin β-receptor (LTβR)-signalling orchestrates lymphoid neogenesis and subsequent tertiary lymphoid structures (TLS)(1,2), associated with severe chronic inflammatory diseases spanning multiple organ systems(3–6). How LTβR-signalling drives chronic tissue damage particularly in the lung, whic...

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Detalles Bibliográficos
Autores principales: Conlon, Thomas M., John-Schuster, Gerrit, Heide, Danijela, Pfister, Dominik, Lehmann, Mareike, Hu, Yan, Ertüz, Zeynep, Lopez, Martin A., Ansari, Meshal, Strunz, Maximilian, Mayr, Christoph, Ciminieri, Chiara, Costa, Rita, Kohlhepp, Marlene Sophia, Guillot, Adrien, Günes, Gizem, Jeridi, Aicha, Funk, Maja C., Beroshvili, Giorgi, Prokosch, Sandra, Hetzer, Jenny, Verleden, Stijn E., Alsafadi, Hani, Lindner, Michael, Burgstaller, Gerald, Becker, Lore, Irmler, Martin, Dudek, Michael, Janzen, Jakob, Goffin, Eric, Gosens, Reinoud, Knolle, Percy, Pirotte, Bernard, Stoeger, Tobias, Beckers, Johannes, Wagner, Darcy, Singh, Indrabahadur, Theis, Fabian J., de Angelis, Martin Hrabé, O’Connor, Tracy O, Tacke, Frank, Boutros, Michael, Dejardin, Emmanuel, Eickelberg, Oliver, Schiller, Herbert B., Königshoff, Melanie, Heikenwalder, Mathias, Yildirim, Ali Önder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718297/
https://www.ncbi.nlm.nih.gov/pubmed/33149305
http://dx.doi.org/10.1038/s41586-020-2882-8