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Programmable m(6)A modification of cellular RNAs with a Cas13-directed methyltransferase
N(6)-methyladenosine (m(6)A) is the most widespread internal mRNA modification in humans. Despite recent progress in understanding the biological roles of m(6)A, the inability to install m(6)A site-specifically in individual transcripts has hampered efforts to elucidate causal relationships between...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718427/ https://www.ncbi.nlm.nih.gov/pubmed/32601430 http://dx.doi.org/10.1038/s41587-020-0572-6 |