Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3

Diabetic kidney disease is known as a major cause of chronic kidney disease and end stage renal disease. Polysulfides, a class of chemical agents with a chain of sulfur atoms, are found to confer renal protective effects in acute kidney injury. However, whether a polysulfide donor, sodium tetrasulfi...

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Detalles Bibliográficos
Autores principales: Sun, Hai-Jian, Xiong, Si-Ping, Cao, Xu, Cao, Lei, Zhu, Meng-Yuan, Wu, Zhi-Yuan, Bian, Jin-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718489/
https://www.ncbi.nlm.nih.gov/pubmed/33279869
http://dx.doi.org/10.1016/j.redox.2020.101813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718489/
https://www.ncbi.nlm.nih.gov/pubmed/33279869
http://dx.doi.org/10.1016/j.redox.2020.101813

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