A systematic review of the “promising zone” design

INTRODUCTION: Sample size calculations require assumptions regarding treatment response and variability. Incorrect assumptions can result in under- or overpowered trials, posing ethical concerns. Sample size re-estimation (SSR) methods investigate the validity of these assumptions and increase the s...

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Detalles Bibliográficos
Autores principales: Edwards, Julia M., Walters, Stephen J., Kunz, Cornelia, Julious, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718653/
https://www.ncbi.nlm.nih.gov/pubmed/33276810
http://dx.doi.org/10.1186/s13063-020-04931-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718653/
https://www.ncbi.nlm.nih.gov/pubmed/33276810
http://dx.doi.org/10.1186/s13063-020-04931-w

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