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Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate
BACKGROUND: Protein synthesis is regulated by the availability of amino acids, the engagement of growth factor signaling pathways, and adenosine triphosphate (ATP) levels sufficient to support translation. Crosstalk between these inputs is extensive, yet other regulatory mechanisms remain to be char...
Autores principales: | Wilde, Blake R., Kaadige, Mohan R., Guillen, Katrin P., Butterfield, Andrew, Welm, Bryan E., Ayer, Donald E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718662/ https://www.ncbi.nlm.nih.gov/pubmed/33292639 http://dx.doi.org/10.1186/s40170-020-00233-6 |
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