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A Genome-Wide RNAi Screen for Enhancers of a Germline Tumor Phenotype Caused by Elevated GLP-1/Notch Signaling in Caenorhabditis elegans

Stem cells are tightly controlled in vivo. Both the balance between self-renewal and differentiation and the rate of proliferation are often regulated by multiple factors. The Caenorhabditis elegans hermaphrodite germ line provides a simple and accessible system for studying stem cells in vivo. In t...

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Detalles Bibliográficos
Autores principales: Dalfó, Diana, Ding, Yanhui, Liang, Qifei, Fong, Alex, Cipriani, Patricia Giselle, Piano, Fabio, Zheng, Jialin C., Qin, Zhao, Hubbard, E. Jane Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718737/
https://www.ncbi.nlm.nih.gov/pubmed/33077477
http://dx.doi.org/10.1534/g3.120.401632