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Chemical-Genetic Interactions with the Proline Analog L-Azetidine-2-Carboxylic Acid in Saccharomyces cerevisiae

Non-proteinogenic amino acids, such as the proline analog L-azetidine-2-carboxylic acid (AZC), are detrimental to cells because they are mis-incorporated into proteins and lead to proteotoxic stress. Our goal was to identify genes that show chemical-genetic interactions with AZC in Saccharomyces cer...

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Detalles Bibliográficos
Autores principales: Berg, Matthew D., Zhu, Yanrui, Isaacson, Joshua, Genereaux, Julie, Loll-Krippleber, Raphaël, Brown, Grant W., Brandl, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718759/
https://www.ncbi.nlm.nih.gov/pubmed/33082270
http://dx.doi.org/10.1534/g3.120.401876