Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology

PURPOSE: Vitronectin, a cell adhesion and spreading factor, is suspected to play a role in the pathogenesis of age-related macular degeneration (AMD), as it is a major component of AMD-specific extracellular deposits (e.g., soft drusen, subretinal drusenoid deposits). The present study addressed the...

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Detalles Bibliográficos
Autores principales: Biasella, Fabiola, Plössl, Karolina, Karl, Claudia, Weber, Bernhard H. F., Friedrich, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718807/
https://www.ncbi.nlm.nih.gov/pubmed/33259607
http://dx.doi.org/10.1167/iovs.61.14.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718807/
https://www.ncbi.nlm.nih.gov/pubmed/33259607
http://dx.doi.org/10.1167/iovs.61.14.2

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