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Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology
PURPOSE: Vitronectin, a cell adhesion and spreading factor, is suspected to play a role in the pathogenesis of age-related macular degeneration (AMD), as it is a major component of AMD-specific extracellular deposits (e.g., soft drusen, subretinal drusenoid deposits). The present study addressed the...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718807/ https://www.ncbi.nlm.nih.gov/pubmed/33259607 http://dx.doi.org/10.1167/iovs.61.14.2 |