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Silencing of the Long Noncoding RNA MYCNOS1 Suppresses Activity of MYCN-Amplified Retinoblastoma Without RB1 Mutation

PURPOSE: MYCNOS (MYCN opposite strand) is co-amplified with MYCN in pediatric cancers, including retinoblastoma. MYCNOS encodes several RNA variants whose functions have not been elucidated in retinoblastoma. Thus, we attempted to identify MYCNOS variants in retinoblastoma and aimed to decipher the...

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Detalles Bibliográficos
Autores principales: Saengwimol, Duangporn, Chittavanich, Pamorn, Laosillapacharoen, Natanan, Srimongkol, Atthapol, Chaitankar, Vijender, Rojanaporn, Duangnate, Aroonroch, Rangsima, Suktitipat, Bhoom, Saisawang, Chonticha, Svasti, Saovaros, Hongeng, Suradej, Kaewkhaw, Rossukon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718827/
https://www.ncbi.nlm.nih.gov/pubmed/33270844
http://dx.doi.org/10.1167/iovs.61.14.8