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Integrative genomic analysis implicates ERCC6 and its interaction with ERCC8 in susceptibility to breast cancer

Up to 30% of all breast cancer cases may be inherited and up to 85% of those may be due to segregation of susceptibility genes with low and moderate risk [odds ratios (OR) ≤ 3] for (mostly peri- and post-menopausal) breast cancer. The majority of low/moderate-risk genes, particularly those with mino...

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Detalles Bibliográficos
Autores principales: Moslehi, Roxana, Tsao, Hui-Shien, Zeinomar, Nur, Stagnar, Cristy, Fitzpatrick, Sean, Dzutsev, Amiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718875/
https://www.ncbi.nlm.nih.gov/pubmed/33277540
http://dx.doi.org/10.1038/s41598-020-77037-7