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Stoichiometry of irreversible ligand binding to a one-dimensional lattice

In this paper we investigate the problem of irreversible binding of a ligand that covers several identical binding sites on a macromolecule with a one-dimensional lattice. Due to steric constraints, irreversible binding or binding with slow kinetics results in partial saturation of the binding sites...

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Detalles Bibliográficos
Autor principal: Tsvetkov, Philipp O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718879/
https://www.ncbi.nlm.nih.gov/pubmed/33277522
http://dx.doi.org/10.1038/s41598-020-77896-0