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Increased expression of LCN2 formed a positive feedback loop with activation of the ERK pathway in human kidney cells during kidney stone formation

Kidney stones are a common threat to the health of elderly patients with a high incidence of disease. However, the specific molecular mechanism of the formation of kidney stones has not been elucidated. Here, we combined signalling molecules with signalling pathways in a double positive circulation...

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Detalles Bibliográficos
Autores principales: Hui, Zhang, Jiang, Zhu, Qiao, Du, Bo, Zhao, Qiyuan, Kang, Shaohua, Bian, Wenbing, Yuan, Wei, Liu, Cheng, Luo, Shuangning, Liu, Zhengyi, Li, Yingyi, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718880/
https://www.ncbi.nlm.nih.gov/pubmed/33277533
http://dx.doi.org/10.1038/s41598-020-75670-w