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Voltage and pH difference across the membrane control the S4 voltage-sensor motion of the Hv1 proton channel
The voltage-gated proton channel Hv1 is expressed in a variety of cells, including macrophages, sperm, and lung epithelial cells. Hv1 is gated by both the membrane potential and the difference between the intra- and extracellular pH (ΔpH). The coupling of voltage- and ∆pH-sensing is such that Hv1 op...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718894/ https://www.ncbi.nlm.nih.gov/pubmed/33277511 http://dx.doi.org/10.1038/s41598-020-77986-z |