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Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions

Biomaterials hold promise for therapeutic applications in the central nervous system (CNS). Little is known about molecular factors that determine CNS foreign body responses (FBRs) in vivo, or about how such responses influence biomaterial function. Here, we probed these factors in mice using a plat...

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Detalles Bibliográficos
Autores principales: OʼShea, Timothy M., Wollenberg, Alexander L., Kim, Jae H., Ao, Yan, Deming, Timothy J., Sofroniew, Michael V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718896/
https://www.ncbi.nlm.nih.gov/pubmed/33277474
http://dx.doi.org/10.1038/s41467-020-19906-3