The matrix metalloproteinase inhibitor marimastat inhibits seizures in a model of kainic acid-induced status epilepticus

An intra-hippocampus injection of kainic acid serves as a model of status epilepticus and the subsequent development of temporal lobe epilepsy. Matrix metalloproteinase-9 (MMP-9) is an enzyme that controls remodeling of the extracellular milieu under physiological and pathological conditions. In res...

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Detalles Bibliográficos
Autores principales: Pijet, Barbara, Konopka, Anna, Rejmak, Emilia, Stefaniuk, Marzena, Khomiak, Danylo, Bulska, Ewa, Pikul, Stanisław, Kaczmarek, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718901/
https://www.ncbi.nlm.nih.gov/pubmed/33277582
http://dx.doi.org/10.1038/s41598-020-78341-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718901/
https://www.ncbi.nlm.nih.gov/pubmed/33277582
http://dx.doi.org/10.1038/s41598-020-78341-y

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