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Nonlinear mechanics of lamin filaments and the meshwork topology build an emergent nuclear lamina
The nuclear lamina—a meshwork of intermediate filaments termed lamins—is primarily responsible for the mechanical stability of the nucleus in multicellular organisms. However, structural-mechanical characterization of lamin filaments assembled in situ remains elusive. Here, we apply an integrative a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718915/ https://www.ncbi.nlm.nih.gov/pubmed/33277502 http://dx.doi.org/10.1038/s41467-020-20049-8 |