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Nonlinear mechanics of lamin filaments and the meshwork topology build an emergent nuclear lamina

The nuclear lamina—a meshwork of intermediate filaments termed lamins—is primarily responsible for the mechanical stability of the nucleus in multicellular organisms. However, structural-mechanical characterization of lamin filaments assembled in situ remains elusive. Here, we apply an integrative a...

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Detalles Bibliográficos
Autores principales: Sapra, K. Tanuj, Qin, Zhao, Dubrovsky-Gaupp, Anna, Aebi, Ueli, Müller, Daniel J., Buehler, Markus J., Medalia, Ohad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718915/
https://www.ncbi.nlm.nih.gov/pubmed/33277502
http://dx.doi.org/10.1038/s41467-020-20049-8