Chloroquine reverses chemoresistance via upregulation of p21(WAF1/CIP1) and autophagy inhibition in ovarian cancer

Overcoming drug-resistance is a big challenge to improve the survival of patients with epithelial ovarian cancer (EOC). In this study, we investigated the effect of chloroquine (CQ) and its combination with cisplatin (CDDP) in drug-resistant EOC cells. We used the three EOC cell lines CDDP-resistant...

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Detalles Bibliográficos
Autores principales: Hwang, Jae Ryoung, Kim, Woo Young, Cho, Young-Jae, Ryu, Ji-Yoon, Choi, Jung-Joo, Jeong, Soo Young, Kim, Myeong-Sun, Kim, Ji Hye, Paik, E. Sun, Lee, Yoo-Young, Han, Hee-Dong, Lee, Jeong-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718923/
https://www.ncbi.nlm.nih.gov/pubmed/33277461
http://dx.doi.org/10.1038/s41419-020-03242-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718923/
https://www.ncbi.nlm.nih.gov/pubmed/33277461
http://dx.doi.org/10.1038/s41419-020-03242-x

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