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In silico molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor

The concept of polypharmacology involves the interaction of drug molecules with multiple molecular targets. It provides a unique opportunity for the repurposing of already‐approved drugs to target key factors involved in human diseases. Herein, we used an in silico target prediction algorithm to inv...

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Detalles Bibliográficos
Autores principales: Ariey‐Bonnet, Jeremy, Carrasco, Kendall, Le Grand, Marion, Hoffer, Laurent, Betzi, Stéphane, Feracci, Mikael, Tsvetkov, Philipp, Devred, Francois, Collette, Yves, Morelli, Xavier, Ballester, Pedro, Pasquier, Eddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718943/
https://www.ncbi.nlm.nih.gov/pubmed/33021050
http://dx.doi.org/10.1002/1878-0261.12810