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Deubiquitinase OTUD6A promotes proliferation of cancer cells via regulating Drp1 stability and mitochondrial fission

Dynamin‐related protein 1 (Drp1) is a cytosolic protein responsible for mitochondrial fission and is essential in the initiation and development of several human diseases, including cancer. However, the regulation of Drp1, especially of its ubiquitination, remains unclear. In this study, we report t...

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Detalles Bibliográficos
Autores principales: Shi, Le, Liu, Jing, Peng, Yunhua, Zhang, Jinfang, Dai, Xiangpeng, Zhang, Shuangxi, Wang, Yongyao, Liu, Jiankang, Long, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718948/
https://www.ncbi.nlm.nih.gov/pubmed/33070427
http://dx.doi.org/10.1002/1878-0261.12825