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Cytotoxic and Antiproliferative Effects of β-Mangostin on Rat C6 Glioma Cells Depend on Oxidative Stress Induction via PI3K/AKT/mTOR Pathway Inhibition

BACKGROUND: Glioma is the most common malignant tumor of the nervous system, which accounts for more than 45% of central nervous system tumors and seriously threatens our health. Because of high mortality rate, limitations, and many complications of traditional treatment methods, new treatment metho...

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Detalles Bibliográficos
Autores principales: Li, Kaiqiang, Wu, Lingling, Chen, Yili, Li, Yuanyuan, Wang, Qianni, Li, Min, Hao, Ke, Zhang, Wei, Jiang, Shanshan, Wang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718963/
https://www.ncbi.nlm.nih.gov/pubmed/33293793
http://dx.doi.org/10.2147/DDDT.S278414