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Intravenous Administration of Triptonide Attenuates CFA-Induced Pain Hypersensitivity by Inhibiting DRG AKT Signaling Pathway in Mice

BACKGROUND: Currently, medical treatment of inflammatory pain is limited by a lack of safe and effective therapies. Triptonide (TPN), a major component of Tripterygium wilfordii Hook.f. with low toxicity, has been shown to have good anti-inflammatory and neuroprotective effects. The present study ai...

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Detalles Bibliográficos
Autores principales: Ling, Yue-Juan, Ding, Ting-Yu, Dong, Fu-Lu, Gao, Yong-Jing, Jiang, Bao-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718987/
https://www.ncbi.nlm.nih.gov/pubmed/33293856
http://dx.doi.org/10.2147/JPR.S275320