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Celecoxib Exerts a Therapeutic Effect Against Demyelination by Improving the Immune and Inflammatory Microenvironments

BACKGROUND: The myelin sheath can be damaged by genetic and/or environmental factors, leading to demyelinating diseases, for which effective treatments are lacking. Recently, cyclooxygenase-2 (COX-2) overexpression was detected in demyelinating lesions both in patients and animal models, opening an...

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Detalles Bibliográficos
Autores principales: Cao, Peipei, Zhang, Hao, Meng, Huiling, Cheng, Yajia, Xu, Haiqi, Zang, Siwen, Li, Zongjin, Cui, Jianlin, Li, Yuhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718997/
https://www.ncbi.nlm.nih.gov/pubmed/33293848
http://dx.doi.org/10.2147/JIR.S282128