TRIM35 mediates protection against influenza infection by activating TRAF3 and degrading viral PB2

Tripartite motif (TRIM) family proteins are important effectors of innate immunity against viral infections. Here we identified TRIM35 as a regulator of TRAF3 activation. Deficiency in or inhibition of TRIM35 suppressed the production of type I interferon (IFN) in response to viral infection. Trim35...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Nan, Jiang, Li, Ye, Miaomiao, Wang, Yihan, Wang, Guangwen, Wan, Xiaopeng, Zhao, Yuhui, Wen, Xia, Liang, Libin, Ma, Shujie, Liu, Liling, Bu, Zhigao, Chen, Hualan, Li, Chengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719147/
https://www.ncbi.nlm.nih.gov/pubmed/32562145
http://dx.doi.org/10.1007/s13238-020-00734-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719147/
https://www.ncbi.nlm.nih.gov/pubmed/32562145
http://dx.doi.org/10.1007/s13238-020-00734-6

Ejemplares similares