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The substrate specificity of the human TRAPPII complex’s Rab-guanine nucleotide exchange factor activity

The TRAnsport Protein Particle (TRAPP) complexes act as Guanine nucleotide exchange factors (GEFs) for Rab GTPases, which are master regulators of membrane trafficking in eukaryotic cells. In metazoans, there are two large multi-protein TRAPP complexes: TRAPPII and TRAPPIII, with the TRAPPII complex...

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Detalles Bibliográficos
Autores principales: Jenkins, Meredith L., Harris, Noah J., Dalwadi, Udit, Fleming, Kaelin D., Ziemianowicz, Daniel S., Rafiei, Atefeh, Martin, Emily M., Schriemer, David C., Yip, Calvin K., Burke, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719173/
https://www.ncbi.nlm.nih.gov/pubmed/33277614
http://dx.doi.org/10.1038/s42003-020-01459-2