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The substrate specificity of the human TRAPPII complex’s Rab-guanine nucleotide exchange factor activity
The TRAnsport Protein Particle (TRAPP) complexes act as Guanine nucleotide exchange factors (GEFs) for Rab GTPases, which are master regulators of membrane trafficking in eukaryotic cells. In metazoans, there are two large multi-protein TRAPP complexes: TRAPPII and TRAPPIII, with the TRAPPII complex...
Autores principales: | Jenkins, Meredith L., Harris, Noah J., Dalwadi, Udit, Fleming, Kaelin D., Ziemianowicz, Daniel S., Rafiei, Atefeh, Martin, Emily M., Schriemer, David C., Yip, Calvin K., Burke, John E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719173/ https://www.ncbi.nlm.nih.gov/pubmed/33277614 http://dx.doi.org/10.1038/s42003-020-01459-2 |
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