ARID1A alterations and their clinical significance in cholangiocarcinoma

BACKGROUND: ARID1A is a member of the SWI/SNF chromatin remodeling complex. It functions as a tumor suppressor and several therapeutic targets in ARID1A-mutated cancers are currently under development, including EZH2. A synthetic lethal relationship between ARID1A and EZH2 has been revealed in sever...

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Detalles Bibliográficos
Autores principales: Namjan, Achira, Techasen, Anchalee, Loilome, Watcharin, Sa-ngaimwibool, Prakasit, Jusakul, Apinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719290/
https://www.ncbi.nlm.nih.gov/pubmed/33344089
http://dx.doi.org/10.7717/peerj.10464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719290/
https://www.ncbi.nlm.nih.gov/pubmed/33344089
http://dx.doi.org/10.7717/peerj.10464

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