Cargando…

ARID1A alterations and their clinical significance in cholangiocarcinoma

BACKGROUND: ARID1A is a member of the SWI/SNF chromatin remodeling complex. It functions as a tumor suppressor and several therapeutic targets in ARID1A-mutated cancers are currently under development, including EZH2. A synthetic lethal relationship between ARID1A and EZH2 has been revealed in sever...

Descripción completa

Detalles Bibliográficos
Autores principales:	Namjan, Achira, Techasen, Anchalee, Loilome, Watcharin, Sa-ngaimwibool, Prakasit, Jusakul, Apinya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2020
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7719290/ https://www.ncbi.nlm.nih.gov/pubmed/33344089 http://dx.doi.org/10.7717/peerj.10464

Ejemplares similares

Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma
por: Tessiri, Supharada, et al.
Publicado: (2022)

Diagnostic and Prognostic Value of Circulating Cell-Free DNA for Cholangiocarcinoma
por: Wintachai, Preawwalee, et al.
Publicado: (2021)

Progranulin modulates cholangiocarcinoma cell proliferation, apoptosis, and motility via the PI3K/pAkt pathway
por: Daya, Minerva, et al.
Publicado: (2018)

In vitro and molecular chemosensitivity in human cholangiocarcinoma tissues
por: Suksawat, Manida, et al.
Publicado: (2019)

Zileuton suppresses cholangiocarcinoma cell proliferation and migration through inhibition of the Akt signaling pathway
por: Khophai, Sasikamon, et al.
Publicado: (2018)

Promoter hypermethylation of early B cell factor 1 (EBF1) is associated with cholangiocarcinoma progression
por: Armartmuntree, Napat, et al.
Publicado: (2021)

Serum IgG as a Marker for Opisthorchis viverrini-Associated Cholangiocarcinoma Correlated with HER2 Overexpression
por: Titapun, Attapol, et al.
Publicado: (2020)

Evaluation of anticancer potential of Thai medicinal herb extracts against cholangiocarcinoma cell lines
por: Promraksa, Bundit, et al.
Publicado: (2019)

Establishment of a Potential Serum Biomarker Panel for the Diagnosis and Prognosis of Cholangiocarcinoma Using Decision Tree Algorithms
por: Kimawaha, Phongsaran, et al.
Publicado: (2021)

Metabolic Phenotyping Predicts Gemcitabine and Cisplatin Chemosensitivity in Patients With Cholangiocarcinoma
por: Suksawat, Manida, et al.
Publicado: (2022)

Upregulation of TCTP is associated with cholangiocarcinoma progression and metastasis
por: Phanthaphol, Nattaporn, et al.
Publicado: (2017)

Mechanisms of oxysterol-induced carcinogenesis
por: Jusakul, Apinya, et al.
Publicado: (2011)

Metabolic Changes of Cholangiocarcinoma Cells in Response to Coniferyl Alcohol Treatment
por: Promraksa, Bundit, et al.
Publicado: (2021)

Imbalanced adaptive responses associated with microsatellite instability in cholangiocarcinoma
por: Loilome, Watcharin, et al.
Publicado: (2017)

Inhibition of endothelial nitric oxide synthase in cholangiocarcinoma cell lines – a new strategy for therapy
por: Suksawat, Manida, et al.
Publicado: (2018)

Inhibitory effect of NVP-BKM120 on cholangiocarcinoma cell growth
por: Padthaisong, Sureerat, et al.
Publicado: (2018)

Curative effect of xanthohumol supplementation during liver fluke-associated cholangiocarcinogenesis: Potential involvement of autophagy
por: Thongchot, Suyanee, et al.
Publicado: (2019)

Opisthorchiasis and cholangiocarcinoma in Southeast Asia: an unresolved problem
por: Hughes, Thomas, et al.
Publicado: (2017)

Prolonged oxidative stress down-regulates Early B cell factor 1 with inhibition of its tumor suppressive function against cholangiocarcinoma genesis
por: Armartmuntree, Napat, et al.
Publicado: (2017)

Mismatch Repair Deficiency Is a Prognostic Factor Predicting Good Survival of Opisthorchis viverrini-Associated Cholangiocarcinoma at Early Cancer Stage
por: Khuntikeo, Natcha, et al.
Publicado: (2023)

Suppression of 14-3-3ζ in cholangiocarcinoma cells inhibits proliferation through attenuated Akt activity, enhancing chemosensitivity to gemcitabine
por: Kittirat, Yingpinyapat, et al.
Publicado: (2018)

Discovery of Serotransferrin Glycoforms: Novel Markers for Diagnosis of Liver Periductal Fibrosis and Prediction of Cholangiocarcinoma
por: Jamnongkan, Wassana, et al.
Publicado: (2019)

CD44 variant‐dependent redox status regulation in liver fluke‐associated cholangiocarcinoma: A target for cholangiocarcinoma treatment
por: Thanee, Malinee, et al.
Publicado: (2016)

Interleukin 25 (IL-25) expression in cholangiocarcinoma
por: Kaewsarabhumi, Supakit, et al.
Publicado: (2020)

High Levels of Serum IgG for Opisthorchis viverrini and CD44 Expression Predict Worse Prognosis for Cholangiocarcinoma Patients after Curative Resection
por: Titapun, Attapol, et al.
Publicado: (2021)

Potential role of HIF-1-responsive microRNA210/HIF3 axis on gemcitabine resistance in cholangiocarcinoma cells
por: Silakit, Runglawan, et al.
Publicado: (2018)

Antifibrotic effect of xanthohumol in combination with praziquantel is associated with altered redox status and reduced iron accumulation during liver fluke-associated cholangiocarcinogenesis
por: Jamnongkan, Wassana, et al.
Publicado: (2018)

Prognostic significance of tumor-infiltrating lymphocytes in predicting outcome of distal cholangiocarcinoma in Thailand
por: Intarawichian, Piyapharom, et al.
Publicado: (2022)

Prognostic Significance of Growth Pattern in Predicting Outcome of Opisthorchis viverrini-Associated Distal Cholangiocarcinoma in Thailand
por: Kunprom, Waritta, et al.
Publicado: (2022)

Urine proteomics study reveals potential biomarkers for the differential diagnosis of cholangiocarcinoma and periductal fibrosis
por: Duangkumpha, Kassaporn, et al.
Publicado: (2019)

Sulfasalazine modifies metabolic profiles and enhances cisplatin chemosensitivity on cholangiocarcinoma cells in in vitro and in vivo models
por: Thanee, Malinee, et al.
Publicado: (2021)

ARID1A Variations in Cholangiocarcinoma: Clinical Significances and Molecular Mechanisms
por: Zhao, Shankun, et al.
Publicado: (2021)

The novel epithelial-mesenchymal transition-related proteins and their therapeutic targets in cholangiocarcinoma: a narrative review
por: Kimawaha, Phongsaran, et al.
Publicado: (2023)

Modification of the eighth AJCC/UICC staging system for perihilar cholangiocarcinoma: An alternative pathological staging system from cholangiocarcinoma-prevalent Northeast Thailand
por: Aphivatanasiri, Chaiwat, et al.
Publicado: (2022)

A Comprehensive Public Health Conceptual Framework and Strategy to Effectively Combat Cholangiocarcinoma in Thailand
por: Khuntikeo, Narong, et al.
Publicado: (2016)

Comparison of a Urine Antigen Assay and Multiple Examinations with the Formalin-Ethyl Acetate Concentration Technique for Diagnosis of Opisthorchiasis
por: Worasith, Chanika, et al.
Publicado: (2023)

Teleconsultation ultrasonography: a new weapon to combat cholangiocarcinoma
por: Chamadol, Nittaya, et al.
Publicado: (2017)

CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression
por: Thanee, Malinee, et al.
Publicado: (2021)

The impact of hypoxia and oxidative stress on proteo-metabolomic alterations of 3D cholangiocarcinoma models
por: Phukhum, Pimpawadee, et al.
Publicado: (2023)

Serum coiled-coil domain containing 25 protein as a potential screening/diagnostic biomarker for cholangiocarcinoma
por: Chanakankun, Ravinnipa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r0sdd34eh8dkbmbod65170u0hd